Composition: 

Ceftazidime, Tazobactam injection

Ceftariz-TZ injection for human critical care consists of ceftazidime and tazobactam. Ceftazidime is a third-generation cephalosporin antibiotic. and tazobactam is a beta-lactamase inhibitor that works as a protector of partner antibiotics. Bacteria are surrounded by a rigid wall made of peptidoglycan, a mesh-like polymer that keeps them from bursting under their own internal pressure. To build and repair this wall, bacteria use enzymes called penicillin-binding proteins (PBPs), which cross-link the peptidoglycan strands together. Ceftazidime inactivates these PBPs, and the bacterial cells die as they grow. This makes it bactericidal medicine.

Tazobactam has a beta-lactam-like structure, so the bacterial enzyme mistakes it for an antibiotic and grabs onto it. But instead of breaking it down and moving on, the enzyme gets stuck. Tazobactam forms a stable, long-lasting bond with the enzyme and permanently disables it. For this reason it is often called a “suicide inhibitor”: it sacrifices itself to knock out the enzyme. 

Benefits

• It is used for respiratory tract infections, which include hospital-acquired pneumonia 
• Effectively kills the growth of bacteria, which eventually kills it; it is crucial for serious infections.
• It is very helpful for skin and soft tissue infections.
• It is used to treat complicated Urinary tract infections.
• It is used for treating life-threatening infections such as abdominal infections, blood stream infections and central nervous system infections.

Common side-effects

• Redness and pain at the injected area
• Diarrhea
• Headache

Instructions to use

• It is an intravenous injection; therefore, it needs to be done by medical professionals
•  Do not self-administer.
• Take the dosage quantity and time as prescribed by the doctor

Precautions

• The prepared solution should be inspected properly make sure that it does not contain any particle, has been discoloured or appears cloudy. 
• Do not reuse syringes or needles.
• Take the medicine only if it is prescribed by the doctor.
• Do not stop taking the medicine unless the doctor suggests stopping. 
• Pregnant and breastfeeding need to be cautious of this medicine

Storage instructions

• Keep it away from sunlight
• Keep it away from children 
• Keep it in a cool and dry place.

Frequently asked questions

Q.1 what is the use of the Ceftariz-TZ injection?

A.1 ceftariz is an antibacterial injection.

Q.2 what should i do if the injection site becomes red and painful?

A.2 mild redness and pain are common symptoms, but these symptoms become severe. Contact your doctor as soon as possible.

Q.3 Can pregnant and breastfeeding women take this medicine?

A.3 tell your doctor if you are pregnant or breastfeeding; there are limited studies that show its effect on pregnant or breastfeeding women.

Q.4 cause diarrhea?

A.4 mild diarrhea is a common symptom of this medicine because it can affect the bacteria inside the stomach.

Q.5 can i use this medicine for a cold and flu?

A.5 no, it is not used for treating minor colds and flu but for more complicated and serious bacterial infections.